• Performs a Probabilistic quotient normalization (PQN) over the dataset to account dilution based in median spectrum. Dieterle, F., Ross, A., Schlotterbeck, G., & Senn, H. (2006). Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in 1H NMR metabonomics. Analytical chemistry, 78(13), 4281-4290. DOI: 10.1021/ac051632c

    Parameters

    Returns { data: number[][]; medianOfQuotients: number[] }

    • {data: Normalized dataset, medianOfQuotients: The median of quotients of each variables}